Abstract: The process flowsheet for high strength steel 82B (/% : 0. 79 ~0. 83C, 0. 15 〜0. 25Si, 0. 72 -0. 80Mn, ≤0.020P, ≤0. 015S, ≤0. 15Cu, 0. 18 ~0. 30Cr) is BOF-LF-165 mm x 165 mm billet casting-hot rolling to Φ 12. 5 mm coil-cold drawing to Φ5. 05 mm products. It is obtained by analysis on cold-drawn fracture of wire rod that the factors including obvious martensite at center of wire rod and network of cementite produced by segregation, large size MgO-CaO-Al₂0₃ - SiO₂ compound inclusions and surface defects lead to cold drawn fracture of wire rod. With the process measures including decreasing the overheating extent of liquid from original 25 ~35 °C to 15 ~25 °C , decreasing the billet casting speed from 1. 80 m/min to 1. 65 m/min, decreasing the amount of secondary cooling water from 0. 80 L/kg to 0. 65 L/kg, increasing the soft argon blowing time from 10 min to 12 min and insuring aging for 3 h at 250 ℃ after rolling, the rating of center porosity ,center segregation and shrinkage cavity of casting billet decreases respectively from 1. 5, 1. 0 and 0. 5 ~ 2. 5 to 0. 5 , 0. 5 and 0 ~ 0. 5, and the total content of inclusions in steel decreases from 0.0035% 〜0.0043% to 0.0017% ~ 0.0021% to basically avoid the occurrence of cold drawn fracture of wire rod.