Abstract: The hot compression of as-cast alloy Ni68Cu28Al is simulated by Gleeble 3500 thermal simulator at defonnation temperature 1 000 ~ 1 150 °C with strain rate of 0.01 ~ 10 s^-1. The flow stress curves of alloy at different conditions are analyzed, the constitutive equation describing the high temperature compression deformation of alloy is established, the constitutive equation is applied to the finite element analysis software DEFORM 3D,and the hot compression process of the alloy is numerically simulated to analyze the changes of strain rate field, strain field and temperature field inside the workpiece. The results show that the hardening effect of as-cast Ni68Cu28Al alloy is very strong during deformation, and the softening effect caused by dynamic recovery and dynamic recrystallization is not obvious, the alloy does not recrystallize completely during deformation,the hot compression process of the alloy has obvious non-uniformity of deformation. Comprehensively considering, the best processing temperature of as-cast Ni68Cu28Al alloy is controlled at 1 000 - 1 100 °C , and the strain rate is about 0. 01 s^-1.