Grade 8.8 non-quenched and tempered fastener hot rolled wire rod based on 10B21 steel was test produced by means of converter → refining furnace → vacuum degassing → square billet continuous casting → heating → rough rolling → medium rolling → finishing rolling → diameter reduction → spinning → XDWP （Xingcheng Direct Water Patenting） cooling → Stelmor air cooling . By controlling the reducing diameter temperature to 813 ℃， the spinning temperature to 828 ℃， and the Stelmor roller table rate to 0.75 m/s， the tensile strength of the hot rolled wire rod reached 680 MPa， the total elongation to 23.6%， section shrinkage to 75%， after continuous XDWP cooling and Stelmor air cooling. Mechanical properties fully met the requirements of GB/T29087―2012. After 1/4 cold top forging and 25% drawing test of large reduction rate， the results met the requirements of fastener users.