In order to obtain GH4169 alloy wire with stable microstructure and properties， the effects of different cold drawing deformation and annealing process on the microstructure and properties of GH4169 alloy wire were studied.Two cold deformation paths were used to prepare

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5.84 mm wires， and the intermediate wires were heat treated at 1 020 ℃/1 min and 1 020 ℃/10 min. Optical microscope analysis of the prepared wire and the sample after heat treatment， EBSD analysis and other methods to observe the grain size and grain boundary characteristics， and compare the mechanical properties of the two kinds of processes of wires， such as tensile strength and plasticity， to establish the relationship between parameters-microstructure-properties.The results showed that the wires’ grains obtained by the process of small deformation + more annealing times were large， which cannot meet the requirements of the index. The grain size of the wire obtained by increasing the deformation and reducing the annealing times was small， and the tensile strength and plasticity were improved. After heat treatment at 1 020 ℃/1 min， there were still many substructures in the wire sample， most of the grains were deformed grains， the proportion of deformed grains was 73%， and the proportion of recrystallized grains was 16.4%；After heat treatment at 1 020 ℃/10 min， the substructure in wire sample almost disappeared， most of the grains were recrystallized grains， the proportion of recrystallized grains was 93%， and the proportion of deformed grains was only 1.13%. Cold-drawn wire was very sensitive to heat treatment， and the recrystallization process could be completed in a very short time. The optimum fabrication process for GH4169 alloy wire is to cold-roll

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8.5 mm wire to

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6.6 mm， then perform an in-line annealing at 1 020 °C， 2.5 m/min， and hydrogen atmosphere， and finally cold-roll to

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5.84 mm.